Animal experimentation and its relevance to man.

Animal experimentation and its relevance to man.

The problem of quantitatively estimating human cancer risk based upon animal carcinogenesis studies is reviewed. Mathematical functions for dose-response relationships are discussed with particular emphasis on multistage models. These models are based upon a single cell somatic mutation theory for the carcinogenesis process. It is shown that the multistage model and others which incorporate bac...

The rights of man and animal experimentation.

Since emotions give contradictory signals about animal experimentation in medical science, man's relationship to animals must be based upon reason. Thomas Aquinas argues that man is essentially different from animals because man's intellectual processes show evidence of an abstract mechanism not possessed by animals. Man's rights arise in association with this essential difference. The conseque...

Refinement) to Animal Experimentation

341 t4 Workshop Report* A Framework Program for the Teaching of Alternative Methods (Replacement, Reduction, Refinement) to Animal Experimentation Mardas Daneshian 1, Mohammad A. Akbarsha 2, Bas Blaauboer 3, Francesca Caloni 4, Pierre Cosson 5, Rodger Curren 6, Alan Goldberg 7, Franz Gruber 8, Frauke Ohl 9, Walter Pfaller 10, Jan van der Valk 11, Pilar Vinardell , Joanne Zurlo , Thomas Hartung ...

Alternatives to Animal Experimentation

This special issue of ALTEX is publicising what the 3R Research Foundation has achieved in the past and what projects are currently underway. This special issue is intended to improve awareness of the projects funded by the Foundation and to provide a training tool. The first section includes updated descriptions of 20 projects from the past ten years. These projects, involving basic research, ...

Alternatives to Animal Experimentation